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The Dune Encyclopedia
This article or section refers to elements that appear exclusively in The Dune Encyclopedia.

Sapho, or more commonly the Juice of Sapho, was a high-energy liquid extracted from the barrier roots of the planet Ecaz. It was used by Mentats.

An issue was addiction to it, an energizing liquid extracted from Ecaz plants, a trap to which Simulationists both in training and in the field were most susceptible

Sapho amplified speculation and extrapolation, but it subjected its users to unpredictable outbursts of emotion or long periods of passivity. The Mentat addict's lethargy led him to neglect the constant updating of information upon which his accuracy depended. A measurable falling-off in reliability was a better indicator of Sapho addiction than its physical signs-ruby colored lips, a reddening of the skin-which could be concealed. Rehabilitation was possible, but relapses into the habit were frequent