Miral Alchem was a woman who survived the Tleilaxu/Corrino take over of Ix from House Vernius, and remained on Ix as an insurgent against the overthrowers.
She did have a Bene Gesserit background and used that to survive in the Xuttuh era of IX. Miral does met up with C'Tair Pilru, brother of D'murr Pilru, who is also a resistance fighter, and the two join forces for a period of time. Eventually, C'Tair and Miral come to love one another while fighting the Tleilaxu occupation. Shortly after the first shipment of explosive wafers from Prince Rhombur Vernius (in exile on Caladan); C'Tair and Miral engineer an attack at four different sites of the Tleilaxu infrastructure on "Xuttuh".
Unfortunately, C'Tair did not see Miral again after this attack. She was captured by the Tleilaxu and changed into an axlotl tank. Coincidentally, Miral's tank is the one that produces the hyper potent and ultimately failed imitation spice under the Tleilaxu Master Hidar Fen Ajidica's Project Amal. However, the manufactured spice is flawed, and Ajidica went mad, and ended up imploding from the inside out due to the substance.
Miral died when the Bene Gesserit Commando Cristane put an explosive disc in her tank and destroyed a large section of the Axlotl Tank created by Ajidica. Cristane occupied her place until the Second Battle of Ix, when Count Hasimir Fenring destroyed all the evidence of the Amal Project that implicated House Corrino's participation.
Miral Alchem is featured in the novels Dune: House Harkonnen and Dune: House Corrino, in the Prelude to Dune Trilogy.