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House Alexin was a Great House of the Imperium. Their homeworld Pelouzen was rendered uninhabitable by atoms and in 4492 AG they were granted the planet Poritrin by the Landsraad. They engaged in a War of Assassins with the House Maros, notable for being the only known War of Assassins in which both sides surrendered due to the damage they had caused each other - effectively a tie.

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