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Chapterhouse: Dune, written by Frank Herbert is the sixth and last novel in the original Dune series. It is also known variously as Chapterhouse Dune, Chapter House Dune and Chapter House: Dune.

The Bene Gesserit still find themselves questioning the Golden Path of humanity set by the God Emperor. Now they must survive the Honored Matres, whose reckless conquest of the Old Empire threatens the Bene Gesserit's survival. The Sisters must reassess their timeless methods: does ultimate survival go beyond calculated manipulation? Is there greater purpose to life than consolidating power?

Concluding the Dune saga

Chapterhouse: Dune ends on a cliffhanger with unanswered questions about the escaped ship, the merging of the Honored Matres and Bene Gesserit, the role of Scytale, the development of Idaho and Teg, what chased the Honored Matres, the role of the Jews, and the identity of the god-like characters in the book's final chapter.

Frank Herbert had planned to write a seventh and final Dune novel, but his death in 1986 meant that the series remains unfinished.

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