5 BG/XD

The Butler family, under the name Corrino, has consolidated a tenuous hold on the human-occupied universe. The head of the Corrino family, Emperor Salvador, lives in splendor on the planet Salusa Secundus with his brother and trusted advisor, Roderick.
Riots still rage over the Orange Catholic Bible of the Commission of Euceminal Translators. Constantly, innocents are executed by mobs, mistaken for the hated Toure Bomoko.
In opposition to the popular movement is the unscrupulous businessman Josef Venport, who holds a near-monopoly on space travel. Advised by his wife Cioba and great-grandmother Norma Cenva, who discovered the secret to creating space-folding "Navigators", Josef plots against his few remaining competitors and funds a secret group of scientific researchers who hold personal grudges against the Butlerians and are willing to salvage and optimize old cymek technology to satisfy their vendettas with Torondo.
On the planet Kepler, war hero Vorian Atreides attempts to keep his neighbors free from the threat of slavers. An attempt to obtain Imperial protection for his planet is successful, but Vorian is sent even deeper into exile by Salvador and Roderick, who are concerned that the Jihad hero may, through his celebrity, incite a rebellion against their authority. He chooses to go to Arrakis, where the Free Men of Dune, who have abandoned the easier life of the Arrakeen villages, continue to thrive in the desert, encountering various enemies and allies during the course of their existence.
On the planet Lankiveil, the Harkonnen family ekes out a lean existence, far from the glory enjoyed by their ancestors after Vorian Atreides disowned the disgraced Abulurd Harkonnen. While the parents have decided to surrender ambition for survival and a humble existence, the two oldest children, Griffin and Valya, seek to rebuild their family fortunes through service to the Landsraad and the Sisterhood on Rossak, respectively.
Vorian's granddaughter Raquella Berto-Anirul, who survived a poisoning that provided her with the memories and mental presences of her female ancestors, leads the Sisterhood of Rossak. She thwarts Butlerian sympathizers within her own ranks, who correctly suspect that Raquella and her inner circle are using computers to manage their breeding index, which comprises an immense amount of family data from across the Imperium. Raquella is aided in these efforts by Sister Valya Harkonnen, who finds her efforts to rebuild her family's glory impeded when the spoiled Princess Anna Corrino (sister to Emperor Salvador and Roderick) is sent to Rossak. Anna, viewed as an embarrassment by the royal family, is meant to learn important skills with the Sisters, but instead follows her own childish ambitions.
Sister Dorotea steals two pills of the Rossak drug that gave Raquella her abilities and encourages Valya to take it alongside her. While Dorotea became the second ever Reverend Mother after taking and surviving it, Valya merely pretends to take it, but keeps the pill. Reverend Mother Dorotea learns of the Sisterhood’s secret computers, and that Raquella is her grandmother. More follow her; including Anna Corrino, who fails to become a Reverend Mother and enters a trance state. Through the new director of the Suk Medical School (and former Rossak Sister) Dr. Ori Zhoma, the Sisterhood also plots against Salvador, who it fears may be the ancestor of a potentially disastrous tyrant.
The Mentat Gilbertus Albans attempts to maintain order in his Mentat school on the planet Lampadas and hide the existence of his old mentor, the robot Erasmus.